CLINICAL TRIAL

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Status: Pending Site Activation

IMAGINE-TBM (A5384): Improved Management with Antimicrobial aGents Isoniazid rifampiciN LinEzolid for TBM

Short Title/Acronym: Imagine TBM

Description:

A Phase II, Randomized, Open-Label Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid and Pyrazinamide versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents with Tuberculous Meningitis.

Start Date: October 24, 2024

Eligibility:

  • Ages 15 and above.
  • This study will enroll Male and Female participants.
  • Who has a defnite, probable or possible TB meningitis diagnosis with or without HIV co-infection.
  • Sample size is a total of 330 participant divided equally into 2 different treatment arms.
  • To Participate in the study kindly reach us via:

     socialworkers@tbhivicr.org.ph
     Call or Text for Smart: 09087751951
     Call or Text for Globe: 09958492471